(양식 1)

【 고분자학회 학회상 포상 지원서 】

[표지]
공모분야	중견학술상
지원자 인적사항	성 명	한 글	한동욱		영 문	Dong-Wook Han
		한 자	韓東旭
	소속기관	기관명	부산대학교
		부서명 (학과명)	광메카트로닉스 공학과		직위/직급	교수
		주 소	부산시 금정구 부산대학로63번길 2
업적요지	본 지원자는 다양한 생체의료용 고분자를 활용하여 생체재료 및 조직공학 연구 분야 발전에 일정 부분 이바지했다고 생각합니다. 2008년 이후 현재까지 총 220여 편(SCIE급 190편 포함) 이상의 논문 실적으로 활발한 연구 활동을 하고 있으며, 관련 분야에서 최상위급 저널인 Nano-Micro Lett., Adv. Compos. Hybrid Mater., ACS Nano, Biomaterials, Nano Converg., Biosens. Bioelectron., J. Hazard. Mater., Mater. Horiz., TrAC, Theranostics (이상 각 1편), Biomater. Res. (9편) 등의 high impact 논문에 교신으로 게재하여 연구의 우수성과 독창성을 인정받고 있습니다. 이와 같이 지난 17년 넘게 연구책임자로 의료용 고분자 소재 및 응용 분야와 고분자학회 발전에 많은 기여를 하고 있다고 판단하여 본 중견학술상에 지원합니다.
상기와 같이 고분자학회 학회상 포상을 지원합니다. 2025. 8. 6 기관명 : 부산대학교 직 위 : 교수 지원자 : 한동욱 (직인)

(양식 2)

1. 인적사항

가. 학력사항 (대학교 이상만 기재)

기 간	학 교 명	전공 및 학위, 지도교수
1993.03~1998.02	연세대학교	생화학/이학사, 김두식
1998.03~2000.02	연세대학교	생체재료학/이학석사, 서 활
2000.03~2004.02	연세대학교	생체재료학/이학박사, 박종철

나. 경력사항 (5개 이내 기재)

기 간	기관명(직위, 직책 등)
2005.10~2008.02	교토대학 재생의과학연구소 박사후 연구원
2008.03~현 재	부산대학교 나노과학기술대학 교수 (현 부학장)
2011.01~현 재	Biomaterials Research 편집위원
2018.01~2019.12	한국고분자학회 운영이사/의료용 분과 총무
2023.01~2025.12	한국생체재료학회 전무이사/감사

다. 수상경력 (최근 3년 이내)

※ 정부 포상, 민간 포상 등 연구개발 업적 관련 수상경력 모두 기재

일 자	수 상 내 용	시 상 기 관
2022.06.29	제32회 과학기술우수논문상	한국과학기술단체총연합회
2023.02.21	Outstanding Reviewer Award	Journal of Nanobiotechnology
2023.09.21	덴티움 우수공헌상	한국생체재료학회
2024.11.21	덴티움 우수논문상	한국생체재료학회
2025.05.16	윤인구학술상	부산대학교

2. 수상후보자 추천인단 명부

성 명	전 공 분 야	세부전공 분야	소 속	비고
김천호	생체재료학	고분자	한국원자력의학원
유자형	화학	고분자	울산과학기술원
박경민	생체재료학	고분자	인천대학교

3. 대표논문의 연구업적 요약서

본 지원자는 생체적합성 고분자와 나노입자를 융합한 체내이식용 스캐폴드를 설계-개발하여 피부, 뼈, 근신경 조직의 재생을 촉진하는 연구를 진행하고 있습니다. 손상 조직을 재건하기 위해 기존에 임상에서 사용되는 이식재는 주로 생체반응성이 낮은 생체비활성 재료 및 자가 · 동종 · 이종 조직을 사용해 왔지만, 감염전파의 위험성, 신규 조직 형성 저하, 공여부의 합병증 및 충분한 양을 체득하기가 어렵다는 한계점이 있습니다. 따라서, 본 지원자는 재료공학 및 생화학적 방법을 기반으로 세포 및 유전자 레벨에서 조직의 재생 거동을 촉진하고, 항염증·항산화 기능성을 부여하여 면역반응을 최소화할 뿐 아니라, 높은 생분해성과 생체적합성을 가지는 기능성 생체재료를 개발하는 것을 목표로 연구를 수행해 왔습니다. 이렇게 개발된 생체재료를 이용하여 3D 바이오프린팅, 전기방사, 표면개질 등의 공정을 거쳐 이식가능한 의료기기를 제작하였고, 신호전달경로 규명 및 동물실험을 통해 그 효용성을 평가해 왔습니다.

이차원 (2D) 나노입자는 높은 비표면적과 특유의 화학적 구조에서 비롯된 전기적·물리화학적 성질을 가지고 있습니다. 이로 인해, 세포의 거동을 조절할 수 있는 여러 생화학적 메커니즘을 유도하는 것으로 알려져 있습니다. 특히, 맥신(MXene)은 탄소 및 티타늄을 기반으로 한 2D 나노물질로서, 높은 생체적합성과 세포 거동 촉진능으로 인해 최근 의생명공학 분야에서 주목받기 시작했습니다. 본 지원자는 맥신 나노입자를 생분해성 고분자와 콜라겐에 함입한 후 전기방사를 통해 복합나노섬유를 제작하여 골조직 재생용 스캐폴드로 응용할 수 있는 연구를 진행하였습니다. 맥신의 풍부한 산소 작용기가 근분화에 필수적인 칼슘 이온 및 포타슘 이온과 선택적으로 결합할 수 있다는 실험 결과에 착안하여, 체적 근육 손실(대규모 외상에 따른 골격근의 20%이상 손실) 치료 · 재생용 나노섬유를 제작하였습니다(Nano-Micro Lett. 2024). 마우스 모델을 이용한 동물실험 결과, 체내에 이식한 맥신 스캐폴드는 빠른 근섬유 다발 재생과 근분화를 촉진한 것을 확인하였고, 근원세포의 생존, 증식, 분화, 근단백질 형성을 촉진하는 신호전달경로(iNOS/SGK1-mediated mTOR-AKT pathway)의 활성을 세계 최초로 규명하였습니다. 후속 연구로서, 기존 2D 지지체의 한계였던 체적 손상 부위의 제한적 충진을 개선하기 위해, 손상 부위의 형태에 정밀하게 맞춰 공간을 채울 수 있는 3D 바이오프린팅 구조체를 제작하였습니다(Theranostics 2025). 본 연구에서 개발한 산소생성형 바이오잉크는 기존 하이드로젤 구조체의 단점인 심부 세포의 사멸을 극복할 수 있는 장점이 있었으며, T세포, B세포, 대식세포의 작용을 조절하는 면역조절기능을 통해 손상 근육의 빠른 재생을 유도할 수 있었습니다. 또한, 탄소나노섬유를 포함한 고분자 나노섬유를 개발하여 상처 치유 및 피부 조직 재생을 촉진한 연구결과를 발표하고(Adv. Compos. Hybrid Mater. 2023), 광생물변조 방법을 사용한 조직 재생에 대한 리뷰 논문(Biomaterials 2024)을 작성한 바 있습니다. 마지막으로, 대표적 2D 탄소나노물질인 그래핀 산화물을 고분자 스캐폴드 위에 코팅하여 섬유아세포와 해마신경세포의 이동 및 분화를 조절하고, 딥러닝 기반 AI 기술을 통해 세포 거동을 평가한 연구 결과(ACS Nano 2024)를 발표하였습니다. 이러한 접근 방법을 통해 기존의 의료용 이식재가 해결하지 못했던 문제들을 극복함으로써, 질병 및 외상에 의한 손상 조직 재생 기술의 비약적인 발전을 가져올 수 있을 것이라 예상됩니다.

4. 연구개발 실적

(1) 업적 총괄 (단위:건)

논문	SCIE 등재 학술지				h-index
	제1저자	공동저자	교신저자	소계	Web of Science	Google Scholar	SCOPUS
	17	77	110	204	54	51	44
특허	국내		국외		기술이전	연구 보고서	저서
	등록		등록
	10		3		1		4

*h-index 증빙자료(화면캡처본) 제출.

(2) 대표논문 목록

제 목	발표지명	Impactor factor	발표 년도	역할(저자)	저자수 (명)	피인용 횟수
Activated carbon nanofiber nanoparticles incorporated electrospun polycaprolactone scaffolds to promote fibroblast behaviors for application to skin tissue engineering	Advanced Composites and Hybrid Materials	21.8	2023	주저자(교신)	9	43
Regulated behavior in living cells with highly aligned configurations on nanowrinkled graphene oxide substrates: Deep learning based on interplay of cellular contact guidance	ACS Nano	16.0	2024	주저자(교신)	6	9
Highly aligned ternary nanofiber matrices loaded with MXene expedite regeneration of volumetric muscle loss	Nano-Micro Letters	36.3	2024	주저자(교신)	8	19
Tailoring photobiomodulation to enhance tissue regeneration	Biomaterials	12.9	2024	주저자(교신)	8	22
3D bioprintable Mg2+-incorporated hydrogels tailored for regeneration of volumetric muscle loss	Theranostics	13.3	2025	주저자(교신)	7	1

*제목 및 저자를 확인할 수 있는 증빙자료 제출.

(3) 총괄연구업적 목록

□ 학술지 논문 – SCIE 등재지에 한함

제 목	발표지명	Impact factor	발표 년도	역할(저자)	저자수 (명)	피인용 횟수
Viability and enzymatic activity of cryopreserved porcine heart valve	Yonsei Medical Journal	2.8	1999	공동	7	17
Determination of a favorable medium for detection of fungal extracellular protease	Biocontrol Science	1.1	1999	공동	6	5
A novel in vitro assessment of tissue valve calcification by a continuous flow type method	Artificial Organs	2.3	2000	공동	4	10
A bone replaceable artificial bone substitute: Morphological and physicochemical characterizations	Yonsei Medical Journal	2.8	2000	공동	3	12
A bone replaceable artificial bone substitute: Cytotoxicity, cell adhesion, proliferation, and alkaline phosphatase activity	Artificial Organs	2.3	2001	공동	5	42
Effective screening medium for the biodegradation of oleic acid by Aspergillus niger	Biocontrol Science	1.1	2001	공동	6	2
A bone replaceable artificial bone substitute: Osteoinduction by combining with bone inducing agent	Artificial Organs	2.3	2001	공동	6	31
Detection of oleic acid biodegradation by fungi	Journal of Microbiology and Biotechnology	3.1	2002	제1저자	6	5
Inactivation of bacteria in seawater by low-amperage electric current	Applied and Environmental Microbiology	3.7	2003	공동	7	103
Liposomal entrapment of cefoxitin to improve cellular viability and function in human saphenous veins	Artificial Organs	2.3	2003	공동	8	5
The effects of recombinant human BMP-7, prepared from COS-7 expression system, on rat newborn calvarial osteoblasts	Yonsei Medical Journal	2.8	2003	공동	6	17
Protective effects of green tea polyphenol against reactive oxygen species-induced oxidative stress in cultured rat calvarial osteoblast	Cell Biology and Toxicology	5.9	2003	공동	7	91
Preservation of human saphenous vein against reactive oxygen species-induced oxidative stress by green tea polyphenol pre-treatment	Artificial Organs	2.3	2003	제1저자	6	24
Fungal sterilization using microwave- induced argon plasma at atmospheric pressure	Journal of Microbiology and Biotechnology	3.1	2004	공동	10	40
Inactivation of Vibrio parahaemolyticus in effluent seawater by alternating-current treatment	Applied and Environmental Microbiology	3.7	2003	공동	9	46
Effects of green tea polyphenol on preservation of human saphenous vein	Journal of Biotechnology	3.9	2004	제1저자	7	35
Enhanced neurite outgrowth of rat neural cortical cells on surface-modified PLGA films	Biotechnology Letters	2.1	2005	제1저자	5	14
Prevention of reactive oxygen species-induced oxidative stress in human microvascular endothelial cells by green tea polyphenol	Toxicology Letters	2.9	2005	공동	5	69
In vitro bioassay of endotoxin using fluorescein as pH indicator in macrophage cell culture system	Yonsei Medical Journal	2.8	2005	공동	8	21
Protection of osteoblastic cells from freeze/thaw cycles-induced oxidative stress by green tea polyphenol	Biotechnology Letters	2.1	2005	제1저자	7	20
Differential biological responses of green tea polyphenol in normal cells vs. cancer cell	Current Applied Physics	3.1	2005	공동	4	51
Effects of β-glucan on proliferation and migration of fibroblasts	Current Applied Physics	3.1	2005	공동	6	50
Long-term preservation of human saphenous vein by green tea polyphenol under physiological conditions	Tissue Engineering	3.5	2005	제1저자	7	50
Evaluation of the extraction method for cytotoxicity test of latex gloves	Yonsei Medical Journal	2.8	2005	공동	7	74
The use of silver-coated ceramic beads for sterilization of Sphingomonas sp. in drinking mineral water	World Journal of Microbiology and Biotechnology	4.2	2005	제1저자	5	29
Analysis of sterilization effect by pulsed dielectric barrier discharge	Journal of Electrostatics	2.0	2006	공동	9	222
Non-frozen preservation of mammalian tissue using green tea polyphenolic compounds.	Biomedical Materials	3.7	2006	제1저자	6	14
Beneficial effects of freezing rate determined by indirect thermophysical calculation on cell viability in cryopreserved tissues	Artificial Cells, Blood Substitutes, and Biotechnology	4.5	2006	제1저자	7	9
Inhibitory effects of epigallocatechin-3-O-gallate on serum-stimulated rat aortic smooth muscle cells via nuclear factor-κB down-modulation	Biochemical and Biophysical Research Communications	2.2	2006	제1저자	7	33
Differential cytokine responses of murine macrophage J774A.1 cells to stainless steel coated with and without hydroxyapatite	Surface and Coatings Technology	6.1	2007	공동	9	5
Degradation of mycotoxins using microwave-induced argon plasma at atmospheric pressure	Surface and Coatings Technology	6.1	2007	공동	9	202
Escherichia coli sterilization and lipopolysaccharide inactivation using microwave-induced argon plasma at atmospheric pressure	Surface and Coatings Technology	6.1	2007	공동	10	70
Stimulated TNF-α release in macrophage and enhanced migration of dermal fibroblast by β- glucan	Current Applied Physics	3.1	2007	공동	7	12
Protection of rabbit kidney from ischemia/reperfusion injury by green tea polyphenol pretreatment	Archives of Pharmacal Research	7.5	2007	공동	6	38
The behavior of vascular smooth muscle cells and platelets onto epigallocatechin gallate-releasing poly(L- lactide-co-ε-caprolactone) as stent-coating materials	Biomaterials	12.9	2008	공동	5	81
Inactivation of Listeria monocytogenes in brine and saline by alternating high-voltage pulsed current	Journal of Microbiology and Biotechnology	3.1	2008	공동	6	6
Surface modification for enhancing behaviors of vascular endothelial cells onto polyurethane films by microwave-induced argon plasma	Surface and Coatings Technology	6.1	2008	공동	11	49
Sterilization of microorganisms in silk fabrics by microwave-induced argon plasma treatment at atmospheric pressure	Surface and Coatings Technology	6.1	2008	공동	9	35
Enhanced wound healing by an epigallocatechin gallate-incorporated collagen sponge in diabetic mice	Wound Repair and Regeneration	3.4	2008	공동	7	134
Time-dependent intracellular trafficking of FITC-conjugated epigallocatechin-3-O-gallate in L-929 cells	Bioorganic and Medicinal Chemistry	3.0	2008	제1저자	4	65
Biochemical and histological evaluations of articular cartilages preserved in cold storage solution containing green tea catechin, EGCG	Tissue Engineering and Regenerative Medicine	4.1	2009	제1저자	3	6
Hydroxyapatite coating on damaged tooth surfaces by immersion	Biomedical Materials	3.7	2009	공동	6	19
Regeneration of a micro-scratched tooth enamel layer by nanoscale hydroxyapatite solution	Bulletin of the Korean Chemical Society	2.2	2009	공동	6	18
Reversible regulation of cell cycle-related genes by epigallocatechin gallate for hibernation of neonatal human tarsal fibroblasts	Cell Transplantation	3.2	2009	공동	5	21
Development of epigallocatechin gallate-eluting polymeric stent and its physicochemical, biomechanical and biological evaluations	Biomedical Materials	3.7	2009	교신	5	15
Cellular responses and behaviors of adipose-derived stem cells onto β-glucan and PLGA composites surface-modified by microwave-induced argon plasma	Macromolecular Research	3.4	2010	제1저자	10	10
Nonfrozen preservation of articular cartilage by epigallocatechin-3-gallate reversibly regulating cell cycle and NF-kB expression	Tissue Engineering Part A	2.9	2010	제1저자	6	12
Effects of cell-seeding methods of human osteoblast culture on biomechanical properties of porous bioceramic scaffold	Biotechnology and Bioprocess Engineering	3.0	2010	교신	5	8
Biological and biomechanical evaluations of osteochondral allografts preserved in cold storage solution containing epigallocatechin gallate	Cell Transplantation	3.2	2010	공동	5	26
The biological activities of (1,3)-(1,6)-β-D-glucan and porous electrospun PLGA membranes containing β-glucan in human dermal fibroblasts and adipose tissue-derived stem cells	Biomedical Materials	3.7	2010	공동	10	64
Underlying mechanism for suppression of vascular smooth muscle cells by green tea polyphenol EGCG released from biodegradable polymers for stent application	Journal of Biomedical Materials Research Part A	3.9	2010	교신	6	20
Selective inhibitory effect of epigallocatechin-3-gallate on migration of vascular smooth muscle cells	Molecules	4.6	2010	제1저자	6	16
Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor- B.	Apoptosis	8.1	2011	제1저자	4	73
Epigallocatechin- 3-gallate regulates cell growth, cell cycle and phosphorylated nuclear factor- B in human dermal fibroblasts	Acta Pharmacologica Sinica	8.4	2011	제1저자	5	44
Direct-current treatment as a safe sterilization method for electrospun biodegradable polymer	Tissue Engineering and Regenerative Medicine	4.1	2011	공동	12	10
Green synthesis of phytochemical-stabilized Au nanoparticles under ambient conditions and their biocompatibility and antioxidative activity	Journal of Materials Chemistry	6.6	2011	교신	7	110
Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups	International Journal of Nanomedicine	6.5	2011	교신	8	212
Cytotoxicity and cell imaging potentials of submicron color-tunable yttria particles	Journal of Biomedical Materials Research Part A	3.9	2012	공동	5	41
Cytotoxicity evaluations of pristine graphene and carbon nanotubes in fibroblastic cells	Journal of the Korean Physical Society	0.9	2012	교신	9	30
Facile synthesis of bifunctional silica-coated core-shell Y2O3:Eu3+,Co2+ composite particles for biomedical applications	RSC Advances	4.6	2012	교신	7	49
Enhanced neurite outgrowth of PC-12 cells on graphene-monolayer-coated substrates as biomimetic cues	Journal of the Korean Physical Society	0.9	2012	교신	7	17
Biocompatibility of nanoscale hydroxyapatite-embedded chitosan films	Bulletin of the Korean Chemical Society	2.3	2012	교신	5	22
Biomechanical assessment of a novel bone lengthening plate system - a cadaveric study	Clinical Biomechanics	1.4	2013	교신	6	3
Validation of the finite element model of the femur and a novel internal distractible plate system	International Journal of Precision Engineering and Manufacturing	3.6	2013	교신	5	2
Biomechanical behavior of two different cervical total disc replacement designs in relation of concavity of articular surfaces: Prodisc-C® vs. Prestige-LP®	International Journal of Precision Engineering and Manufacturing	3.6	2013	공동	6	31
Cryoprotection of fibroblasts by carboxylated poly-L-lysine upon repeated freeze/thaw cycles	CryoLetters	0.9	2013	교신	8	13
Mesoporous silica with fibrous morphology: A multifunctional core-shell platform for biomedical applications	Nanotechnology	2.8	2013	공동	7	53
Difference between toxicities of iron oxide magnetic nanoparticles with various surface-functional groups against human normal fibroblasts and fibrosarcoma cells	Materials	3.2	2013	교신	6	75
Cell imaging and DNA delivery in fibroblastic cells by conjugated polyelectrolytes	Biotechnology and Applied Biochemistry	2.7	2013	교신	10	8
Enhanced neural cell adhesion and neurite outgrowth on graphene-based biomimetic substrates	BioMed Research International	2.3	2014	교신	8	102
Promotion of full-thickness wound healing using epigallocatechin-3-O-gallate/poly (lactic-co-glycolic acid) membrane as temporary wound dressing	Artificial Organs	2.3	2014	공동	7	41
Human hair keratin and its-based biomaterials for biomedical applications	Tissue Engineering and Regenerative Medicine	4.1	2014	공동	7	177
Ultrafine PEG-capped gadolinia nanoparticles: cytotoxicity and potential biomedical applications for MRI and luminescent imaging	RSC Advances	4.6	2014	교신	5	33
PLGA nanofiber membranes loaded with epigallocatechin-3-O-gallate beneficial to prevention of postsurgical adhesions	International Journal of Nanomedicine	6.5	2014	교신	8	61
RGD peptide-displaying M13 bacteriophage/PLGA nanofibers as cell-adhesive matrices for smooth muscle cells	Journal of the Korean Physical Society	0.9	2015	교신	10	12
Highly sensitive detection of epidermal growth factor receptor expression levels using a capacitance sensor	Sensors and Actuators B: Chemical	7.7	2015	공동	9	19
Stimulated myoblast differentiation on graphene oxide-impregnated PLGA-collagen hybrid fiber matrices	Journal of Nanobiotechnology	12.6	2015	교신	9	169
Human hair keratin-based biofilm for potent application to periodontal tissue regeneration	Macromolecular Research	3.4	2015	공동	11	29
Biomimetic hybrid nanofiber sheets composed of RGD peptide-decorated PLGA as cell-adhesive substrates.	Journal of Functional Biomaterials	5.2	2015	교신	8	33
Fabrication of carbon coated gadolinia particles for dual-mode magnetic resonance MR and fluorescence imaging	Journal of Advanced Ceramics	16.6	2015	공동	5	15
Reduced graphene oxide-coated hydroxyapatite composites stimulate spontaneous osteogenic differentiation of human mesenchymal stem cells	Nanoscale	5.1	2015	교신	8	185
Transdermal treatment of the surgical and burned wound skin via phytochemical-capped gold nanoparticles	Colloids and Surfaces B: Biointerfaces	5.6	2015	공동	7	52
Stimulating effect of graphene oxide on myogenesis of C2C12 myoblasts on PLGA/RGD nanofiber matrices	Journal of Biological Engineering	6.5	2015	교신	9	82
Synergistic effects of reduced graphene oxide and hydroxyapatite on osteogenic differentiation of MC3T3-E1 preosteoblasts	Carbon	11.6	2015	교신	8	78
Stimulated myogenic differentiation of C2C12 murine myoblasts by graphene oxide	Journal of the Korean Physical Society	0.9	2015	교신	8	11
Inhibition of mitochondrial Na+-Ca2+ exchange by CGP-37157 attenuates BCR-mediated apoptosis in DT40 B lymphocyte	Journal of the Korean Physical Society	0.9	2015	교신	6	0
Enhanced osteogenesis by reduced graphene oxide/hydroxyapatite nanocomposites	Scientific Reports	3.9	2015	교신	9	359
Multicolor nanoprobes based on silica-coated gadolinium oxide nanoparticles with highly reduced toxicity	RSC Advances	4.6	2016	공동	10	33
In situ forming gelatin/graphene oxide hydrogels for facilitated C2C12 myoblast differentiation	Applied Spectroscopy Reviews	5.4	2016	교신	10	39
Graphene oxide-coated guided bone regeneration membranes with enhanced osteogenesis: Spectroscopic analysis and animal study	Applied Spectroscopy Reviews	5.4	2016	교신	12	67
Golgi polarization effects on infiltration of mesenchymal stem cells into electrospun scaffolds by fluid shear stress: Analysis by confocal microscopy and Fourier transform infrared spectroscopy	Applied Spectroscopy Reviews	5.4	2016	공동	8	4
Enhancement of matrix metalloproteinase-2 (MMP-2) as a potential chondrogenic marker during chondrogenic differentiation of human adipose-derived stem cells	International Journal of Molecular Sciences	4.9	2016	공동	11	23
A nonconventional approach to patterned nanoarrays of DNA strands for template-assisted assembly of polyfluorene nanowires	Small	12.1	2016	공동	8	15
Cell migration according to shape of graphene oxide micropatterns	Micromachines	3.0	2016	교신	12	28
Biomechanical assessment of a novel lengthening plate for distraction osteogenesis: A finite element study.	Biomedical Engineering Letters	2.8	2016	교신	6	2
Optimum conditions for the fabrication of zein/Ag composite nanoparticles from ethanol/H2O co-solvents using electrospinning	Nanomaterials	4.3	2016	공동	7	27
Hyaluronic acid/PLGA core/shell fiber matrices loaded with EGCG beneficial to diabetic wound healing	Advanced Healthcare Materials	9.6	2016	교신	13	124
Eu, Gd-codoped yttria nanoprobes for optical and T1-weighted magnetic resonance imaging	Nanomaterials	4.3	2017	교신	10	33
RGD peptide and graphene oxide co-functionalized PLGA nanofiber scaffolds for vascular tissue engineering	Regenerative Biomaterials	8.1	2017	교신	10	92
Toxicity and T2-weighted magnetic resonance imaging potentials of holmium oxide nanoparticles	Nanomaterials	4.3	2017	교신	5	42
The effect of reduced graphene oxide-coated biphasic calcium phosphate bone graft material on osteogenesis	International Journal of Molecular Sciences	4.9	2017	공동	10	62
Multifaceted biomedical applications of functional graphene nanomaterials to coated substrates, patterned arrays and hybrid scaffolds	Nanomaterials	4.3	2017	교신	7	38
Dicalcium phosphate combined with graphene synergistically increases osteogenic differentiation in vitro	Coatings	2.8	2018	교신	8	20
Nanocomposite scaffolds for myogenesis revisited: Functionalization with carbon nanomaterials and spectroscopic analysis	Applied Spectroscopy Reviews	5.4	2018	교신	8	6
Exploring the use of impedance spectroscopy in relaxation and electrochemical studies	Applied Spectroscopy Reviews	5.4	2018	공동	7	8
Recent progress in organic photorefractive materials	Applied Spectroscopy Reviews	5.4	2018	공동	5	11
Aligned laminin core-polydioxanone/collagen shell fiber matrices effective for neuritogenesis	Scientific Reports	3.9	2018	교신	8	43
Improved bioactivity of GUMMETAL®, Ti59Nb36Ta2Zr3O0.3, via formation of nanostructured surfaces	Journal of Tissue Engineering	7.0	2018	공동	6	18
Three-dimensional graphene oxide-coated polyurethane foams beneficial to myogenesis	Journal of Biomaterials Science, Polymer Edition	3.6	2018	교신	6	52
Dose- and time-dependent cytotoxicity of layered black phosphorus in fibroblastic cells	Nanomaterials	4.3	2018	교신	6	77
Fabrication of self-assembled nanoporous structures from a self-templating M13 bacteriophage	ACS Applied Nano Materials	5.5	2018	교신	8	7
Cordyceps militaris grown on germinated soybean suppresses KRAS-driven colorectal cancer by inhibiting the RAS/ERK pathway	Nutrients	5.0	2019	공동	6	12
Enhanced osteogenic differentiation of human mesenchymal stem cells on Ti surfaces with electrochemical nanopattern formation	Materials Science & Engineering C	8.1	2019	공동	9	51
Engineered "coffee-rings" of reduced graphene oxide as ultrathin contact guidance to enable patterning of living cells	Materials Horizons	10.7	2019	교신	9	47
Virus-incorporated biomimetic nanocomposites for tissue regeneration	Nanomaterials	4.3	2019	교신	8	25
Protective effects of melon extracts on bone strength, mineralization, and metabolism in rats with ovariectomy-induced osteoporosis	Antioxidants	6.6	2019	교신	9	18
Toxicity of zero- and one-dimensional carbon nanomaterials	Nanomaterials	4.3	2019	교신	9	84
Research progress of M13 bacteriophage-based biosensors	Nanomaterials	4.3	2019	공동	6	51
Transdermal delivery of Minoxidil using HA-PLGA nanoparticles for the treatment in alopecia	Biomaterials Research	9.6	2019	공동	7	59
Comparison of cytotoxicity of black phosphorus nanosheets in different types of fibroblasts	Biomaterials Research	9.6	2019	교신	7	70
Ternary nanofiber matrices composed of PCL/collagen/black phosphorus to enhance osteodifferentiation	Journal of Industrial and Engineering Chemistry	6.0	2019	교신	12	24
Volume adaptation controls stem cell mechanotransduction	ACS Applied Materials & Interfaces	8.2	2019	공동	16	90
Hierarchical cluster analysis of medical chemicals detected by a bacteriophage-based colorimetric sensor array	Nanomaterials	4.3	2020	교신	12	33
Rapid synthesis of nontoxic and photostable carbon nanoparticles for bioimaging applications	Materials Letters	2.7	2020	교신	7	31
Stem cell mechanosensation on gelatin methacrylol (GelMA) stiffness gradient hydrogels	Annals of Biomedical Engineering	5.4	2020	공동	11	127
Virus-based nanomaterials and nanostructures	Nanomaterials	4.3	2020	교신	2	16
Mechanical assessment of fatigue characteristics between single- and multi-directional cyclic loading modes on dental implant system.	Materials	3.2	2020	공동	9	19
Hyaluronic acid- based theranostic nanomedicines for targeted cancer therapy	Cancers	4.4	2020	교신	5	134
Au nanozyme-driven antioxidation for preventing frailty	Colloids and Surfaces B: Biointerfaces	5.6	2020	교신	11	16
Two-dimensional theranostic nanomaterials in cancer treatment: State of the art and perspectives	Cancers	4.4	2020	교신	4	33
State of the art biocompatible gold nanoparticles for cancer theragnosis	Pharmaceutics	5.5	2020	교신	4	141
Advanced techniques for skeletal muscle tissue engineering and regeneration	Bioengineering	3.7	2020	교신	6	53
Fluorescent carbon-based nanostructures for bioimaging applications	Frontiers in Chemistry	4.2	2020	교신	2	4
Increased neuritogenesis on ternary nanofiber matrices of PLCL and laminin decorated with black phosphorus	Journal of Industrial and Engineering Chemistry	6.0	2020	교신	8	29
Recent trends in photoacoustic imaging techniques for 2D nanomaterials-based phototherapy	Biomedicines	3.9	2021	교신	6	31
Reduced graphene oxide coating enhances osteogenic differentiation of human mesenchymal stem cells on Ti surfaces	Biomaterials Research	9.6	2021	교신	7	76
Development of two-dimensional nanomaterials based electrochemical biosensors on enhancing the analysis of food toxicants	International Journal of Molecular Sciences	4.9	2021	교신	6	36
Three-dimensional printable gelatin hydrogels incorporating graphene oxide to enable spontaneous myogenic differentiation	ACS Macro Letters	5.2	2021	교신	8	52
A critical review on genotoxicity potential of low dimensional nanomaterials	Journal of Hazardous Materials	11.3	2021	교신	6	22
Carbon dots-mediated fluorescent scaffolds: Recent trends in image-guided tissue engineering applications	International Journal of Molecular Sciences	4.9	2021	교신	6	41
Spontaneously promoted osteogenic differentiation of MC3T3-E1 preosteoblasts on ultrathin layers of black phosphorus	Materials Science & Engineering C	8.1	2021	교신	10	26
Potential of carbon-based nanocomposites for dental tissue engineering and regeneration	Materials	3.2	2021	교신	8	11
Investigation of colorimetric biosensor array based on programable surface chemistry of M13 bacteriophage towards artificial nose for volatile organic compound detection: From basic properties of the biosensor to practical application	Biosensors and Bioelectronics	10.5	2021	교신	10	38
Recent trends in exhaled breath diagnosis using an artificial olfactory system	Biosensors	5.6	2021	교신	8	41
Differential cellular interactions and responses to ultrathin micropatterned graphene oxide arrays with or without ordered in turn RGD peptide films	Applied Surface Science	6.9	2021	교신	6	16
A simple route to the complexation of lutein with reduced graphene oxide nanocarriers and antioxidant protection against blue light	International Journal of Nanomedicine	6.5	2021	공동	6	18
Single-ion conducting polymer electrolytes as a key jigsaw piece for the next-generation battery applications	Chemical Science	7.4	2021	공동	4	126
Polyphenol-loaded electrospun nanofiber in bone tissue engineering and regeneration	Biomaterials Research	9.6	2021	교신	8	58
Electrospun one dimensional (1D) pseudocapacitive nanorods embedded carbon nanofiber as positrode and graphene wrapped carbon nanofiber as negatrode for enhanced electrochemical energy storage	Journal of Energy Storage	9.8	2022	공동	7	32
Recent advances of point-of-care devices integrated with molecularly imprinted polymers-based biosensors: From biomolecule sensing design to intraoral fluid testing	Biosensors	5.6	2022	공동	6	79
Enhanced osseointegration of dental implants with reduced graphene oxide coating	Biomaterials Research	9.6	2022	교신	9	59
The predominant factor influencing cellular behavior on electrospun nanofibrous scaffolds: Wettability or surface morphology?	Materials & Design	7.9	2022	교신	7	42
Combinatorial wound healing therapy utilizing adhesive nanofibrous membrane equipped with wearable LED patches for photobiomodulation	Science Advances	12.5	2022	공동	11	67
In-situ crosslinkable collagen-based hydrogels for 3D printing of dermis-mimetic constructs	ECS Journal of Solid State Science and Technology	2.2	2022	교신	8	13
Designing inorganic nanoparticles into computed tomography and magnetic resonance (CT/MR) imaging-guidable photomedicines.	Materials Today Nano	8.2	2022	교신	6	22
State of the art in carbon nanomaterials for photoacoustic imaging	Biomedicines	3.9	2022	교신	6	34
A phage- and colorimetric sensor-based artificial nose model for banana ripening analysis	Sensors and Actuators B: Chemical	7.7	2022	교신	8	30
Artificial olfactory sensor technology that mimics the olfactory mechanism: a comprehensive review	Biomaterials Research	9.6	2022	교신	7	87
Ternary MXene-loaded PLCL/collagen nanofibrous scaffolds to promote spontaneous osteogenic differentiation	Nano Convergence	11.0	2022	교신	7	36
3D printing of skin equivalents with hair follicle structures and epidermal-papillary-dermal multi-layers using gelatin/hyaluronic acid hydrogels	Chemistry - An Asian Journal	3.3	2022	교신	10	47
Terbium and barium codoped mesoporous silica nanoparticles with enhanced optical properties	Materials Letters	2.7	2022	교신	8	7
Upconversion nanomaterials and delivery systems for smart photonic medicines and healthcare devices	Advanced Drug Delivery Reviews	17.6	2022	공동	8	31
Dental implants with electrochemical nanopattern formation to increase osseointegration	Journal of Industrial and Engineering Chemistry	6.0	2022	교신	8	3
Advances and innovations of 3D bioprinting skin	Biomolecules	4.8	2023	교신	8	53
Activated carbon nanofiber nanoparticles incorporated electrospun polycaprolactone scaffolds to promote fibroblast behaviors for application to skin tissue engineering	Advanced Composites and Hybrid Materials	21.8	2023	교신	9	43
State-of-the-art techniques for promoting tissue regeneration: Combination of three-dimensional bioprinting and carbon nanomaterials	International Journal of Bioprinting	6.0	2023	교신	8	19
Improved antibacterial activity of 3D wrinkled graphene oxide films implemented with irreversibly shrinkable shape-memory polymer substrate	Environmental Science: Nano	5.1	2023	공동	4	7
Investigation on centrifugally spun fibrous of PCL/3-methyl mannoside mats for wound healing application	Polymers	4.9	2023	교신	9	7
3D bioprinting of human mesenchymal stem cells-laden hydrogels incorporating MXene for spontaneous osteodifferentiation	Heliyon	3.6	2023	교신	7	39
The cytoprotective effects of baicalein on H2O2-induced ROS by maintaining mitochondrial homeostasis and cellular tight junction in HaCaT keratinocytes	Antioxidants	6.6	2023	교신	3	25
A systematic study on the use of multifunctional nanodiamonds for neuritogenesis and super-resolution imaging	Biomaterials Research	9.6	2023	교신	6	6
Terbium-doped carbon dots (Tb-CDs) as a novel contrast agent for efficient X-ray attenuation	RSC Advances	4.6	2023	공동	11	9
Spontaneous osteogenic differentiation of human mesenchymal stem cells by tuna-bone-derived hydroxyapatite composites with green tea polyphenol-reduced graphene oxide	Cells	5.2	2023	교신	9	10
Thyroid-friendly soft materials as 3D cell culture tool for stimulating thyroid cell function	Small	12.1	2023	공동	13	0
3D printed membranes of polylactic acid and graphene oxide for guided bone regeneration	Nanoscale Advances	4.6	2023	교신	10	17
The effectiveness of a novel air-barrier device for an aerosol reduction in dental environment: computational fluid dynamics simulation	Bioengineering	3.7	2023	공동	9	0
Recent trends in macromolecule-based approaches for hair loss treatment	Macromolecular Bioscience	4.1	2023	교신	8	3
Recent advances in marine biomaterials tailored and primed for the treatment of damaged soft tissues	Marine Drugs	5.4	2023	교신	6	7
Mobile point-of-care-device using molecularly imprinted polymer-based chemosensors targeting interleukin-1β biomarker	Biosensors	5.6	2023	공동	9	12
MXene and Xene: promising frontier beyond graphene in tissue engineering and regenerative medicine	Nanoscale Horizons	6.6	2024	교신	5	13
Highly aligned ternary nanofiber matrices loaded with MXene expedite regeneration of volumetric muscle loss	Nano-Micro Letters	36.3	2024	교신	8	19
Regulated behavior in living cells with highly aligned configurations on nanowrinkled graphene oxide substrates: Deep learning based on interplay of cellular contact guidance	ACS Nano	16.0	2024	교신	6	9
Skeletal muscle regeneration with 3D bioprinted hyaluronate/gelatin hydrogels incorporating MXene nanoparticles	International Journal of Biological Macromolecules	8.5	2024	교신	7	20
Nanofibrous materials-reinforced printable ink for enhanced cell proliferation and tissue regeneration	Bioengineering	3.7	2024	교신	3	2
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	Trends in Analytical Chemistry	12.0	2024	교신	6	15
Extraction of γ-chitosan from insects and fabrication of PVA/γ-chitosan/kaolin nanofiber wound dressings with hemostatic properties	Discover Nano	4.5	2024	공동	7	7
Cold-responsive hyaluronated upconversion nanoplatform for transdermal cryo-photodynamic cancer therapy	Advanced Science	14.1	2024	공동	12	20
Influence of esterified kraft lignin as an interfacial compatibilizer on mechanical properties of acrylonitrile-butadiene-styrene/basalt fiber composites	Journal of Applied Polymer Science	2.8	2024	교신	6	2
Advances and innovations of hybrid nanofiber-based matrices for dental tissue engineering	Nanocomposites	3.7	2024	교신	6	1
Tailoring photobiomodulation to enhance tissue regeneration	Biomaterials	12.9	2024	교신	8	22
Studies on cytocompatibility of human dermal fibroblasts on carbon nanofiber nanoparticle-containing bioprinted constructs	Discover Nano	4.5	2024	교신	6	2
Ionic liquid-based extraction of fulvic-like substances from wood sawdust: Reproducing unique biological activities of fulvic acids using renewable natural sources	Journal of Agricultural and Food Chemistry	6.2	2024	공동	11	2
Harnessing 3D printed highly porous Ti-6Al-4V scaffolds coated with graphene oxide to promote osteogenesis	Biomaterials Science	5.7	2024	교신	9	3
Advancements in nanobiosensor technologies for in-vitro diagnostics to point of care testing	Heliyon	3.6	2024	교신	5	4
Harnessing the intradermal delivery of hair follicle dermal papilla cell spheroids for hair follicle regeneration in nude mice	Biomaterials Research	9.6	2024	교신	9	1
3D bioprintable Mg2+-incorporated hydrogels tailored for regeneration of volumetric muscle loss	Theranostics	13.3	2025	교신	7	1
N-benzyl-N-methyldecane-1-amine, derived from garlic ameliorates UVB-induced photoaging in HaCaT cells and SKH-1 hairless mice	Scientific Reports	3.9	2025	공동	16	2
The potential of nanofibrous matrices in muscular regeneration	Nanomedicine	3.9	2025	교신	2	0
Cellular behaviors of human dermal fibroblasts on pyrolytically stripped carbon nanofiber's surface	Macromolecular Bioscience	4.1	2025	교신	5	0
Versatile and marvelous potentials of polydeoxyribonucleotide for tissue engineering and regeneration	Biomaterials Research	9.6	2025	교신	6	2
High spectral energy density all-fiber nanosecond pulsed 1.7 μm light source for photoacoustic microscopy	Photoacoustics	6.8	2025	공동	10	0
Combinatorial glyoxal cross-linking and glutamic acid capping for mitigating calcification in bovine pericardium	Chemistry - An Asian Journal	3.3	2025	교신	9	0
A wearable electrochemical biosensor for salivary detection of periodontal inflammation biomarkers: Molecularly imprinted polymer sensor with deep learning integration	Advanced Science	14.1	2025	공동	8	0
Zinc ion-releasing gelatin-based bioadhesives for wound management	Small Structures	11.3	2025	교신	4	0

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제 목	등록번호	등록년도	등록처	역할
Antifungal agents and composition for external use	JP2008-007464A	2008	일본	공동
파이토케미컬로 표면처리된 금나노입자를 유효성분으로 함유하는 피부노화방지용 화장료 조성물	10-1333209	2013	한국	공동
수산화아파타이트와 환원 그래핀 옥사이드 복합입자를 유효성분으로 하는 골충진제	10-1367143	2014	한국	주
조직재생용 생분해성 나노섬유시트의 제조방법 및 이에 의하여 제조된 나노섬유시트	10-1636778	2016	한국	주
케라틴과 EGCG 복합체를 함유하는 조성물 및 그 제조방법	10-1746219	2017	한국	공동
골유도재생 차폐막 및 그 제조방법	10-1803741	2017	한국	주
신경도관 제조방법	10-2041231	2019	한국	공동
Preparing method of nerve conduits	US 11471563 B2	2022	미국	공동
골조직 재생 지지체 및 이의 제조 방법	10-2364168	2022	한국	주
3D 프린팅용 바이오 잉크 및 이를 이용한 구조체의 제조방법	10-2412359	2022	한국	주
Colorimetric biosensor, discoloration kit, and sensing method using the same	US 2022/0291224 A1	2022	미국	공동
히알루론산-콜라겐 기반 3D 바이오잉크 조성물	10-2634670	2024	한국	주
목질계 바이오매스로부터 풀빅산 유사체를 추출하는 방법 및 이에 의해 추출된 풀빅산 유사체	10-2703227	2024	한국	공동

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